Publications | Protein Homeostasis

Protein Homeostasis Lab

Munan, S., Ali, M., Yadav, R., Mapa, K. and Samata, A. PET- and ICT-Based Ratiometric Probe: An Unusual Phenomenon of Morpholine-Conjugated Fluorophore for Mitochondrial pH Mapping during Mitophagy, August 2022, Analytical Chemistry 94(33) DOI: 10.1021/acs.analchem.2c02177

Sarkar, R., Rao, K. B. N., Jha, M. P., & Mapa, K. (2022). Endoplasmic reticulum-unfolded protein response pathway modulates the cellular response to mitochondrial proteotoxic stress. Cell Stress and Chaperones, 27(3), 241–256. https://doi.org/10.1007/s12192-022-01264-2

Baruah, M., Jana, A., Ali, M., Mapa, K., & Samanta, A. (2022). An efficient PeT based fluorescent probe for mapping mitochondrial oxidative stress produced <i>via</i> the Nox2 pathway. Journal Of Materials Chemistry B, 10(13), 2230-2237. doi: 10.1039/d2tb00356b

Munan, S., Kottarathil, S., Joseph, M., Jana, A., Ali, M., & Mapa, K. et al. (2022). IndiFluors: A New Full-Visible Color-Tunable Donor–Acceptor–Donor (D<sub>1</sub>–A–D<sub>2</sub>) Fluorophore Family for Ratiometric pH Imaging during Mitophagy. ACS Sensors. doi: 10.1021/acssensors.1c02381

Ali, M., Rajurkar, J., Majumder, P., Jha, M., Sarkar, R., & Mapa, K. (2021). Possible Therapeutic Intervention Strategies for COVID-19 by Manipulating the Cellular Proteostasis Network. Coronavirus Therapeutics – Volume I, 125-147. doi: 10.1007/978-3-030-85109-5_8

Sadat, A., Tiwari, S., & Mapa, K. (2021). Protocol for Spontaneous and Chaperonin-assisted in vitro Refolding of a Slow-folding Mutant of GFP, sGFP. BIO-PROTOCOL, 11(14). doi: 10.21769/bioprotoc.4099

Ali, M., Boosi Narayana Rao, K., Majumder, P., Sarkar, R., & Mapa, K. (2021). Alterations in inter-organelle crosstalk and Ca2+ signaling through mitochondria during proteotoxic stresses. Mitochondrion, 57, 37-46. doi: 10.1016/j.mito.2020.12.003

Sadat, A., Tiwari, S., Verma, K., Ray, A., Ali, M., & Upadhyay, V. et al. (2020). GROEL/ES Buffers Entropic Traps in Folding Pathway during Evolution of a Model Substrate. Journal Of Molecular Biology, 432(20), 5649-5664. doi: 10.1016/j.jmb.2020.08.015

Kumar, V., Peter, J., Sagar, A., Ray, A., Jha, M., & Rebeaud, M. et al. (2019). Interdomain communication suppressing high intrinsic <scp>ATP</scp> ase activity of Sse1 is essential for its co‐disaggregase activity with Ssa1. The FEBS Journal, 287(4), 671-694. doi: 10.1111/febs.15045

Ghosh, A., Gangadharan, A., Verma, M., Das, S., Matai, L., & Dash, D. et al. (2019). Cellular responses to proteostasis perturbations reveal non-optimal feedback in chaperone networks. Cellular And Molecular Life Sciences, 76(8), 1605-1621. doi: 10.1007/s00018-019-03013-8

Kumar, V., & Mapa, K. (2018). Hsp70: A Multi-Tasking Chaperone at the Crossroad of Cellular Proteostasis. Regulation Of Heat Shock Protein Responses, 251-274. doi: 10.1007/978-3-319-74715-6_10

Kumar, V., Peter, J., Sagar, A., Ray, A., Ashish, & mapa, k. (2017). Atypical domain communication and domain functions of a Hsp110 chaperone. doi: 10.1101/220798

Banerjee, R., Jayaraj, G., Peter, J., Kumar, V., & Mapa, K. (2016). Monitoring conformational heterogeneity of the lid of DnaK substrate-binding domain during its chaperone cycle. The FEBS Journal, 283(15), 2853-2868. doi: 10.1111/febs.13769

Banerjee, R., Jayaraj, G., Peter, J., Kumar, V., & Mapa, K. (2016). Monitoring conformational heterogeneity of the lid of DnaK substrate-binding domain during its chaperone cycle. The FEBS Journal, 283(15), 2853-2868. doi: 10.1111/febs.13769

Kumar, S., Mapa, K., & Maiti, S. (2014). Understanding the Effect of Locked Nucleic Acid and 2′-<i>O</i>-Methyl Modification on the Hybridization Thermodynamics of a miRNA–mRNA Pair in the Presence and Absence of AfPiwi Protein. Biochemistry, 53(10), 1607-1615. doi: 10.1021/bi401677d

Sikor, M., Mapa, K., von Voithenberg, L., Mokranjac, D., & Lamb, D. (2013). Real-time observation of the conformational dynamics of mitochondrial Hsp70 by spFRET. The EMBO Journal, 32(11), 1639-1649. doi: 10.1038/emboj.2013.89

Agarwala, P., Pandey, S., Mapa, K., & Maiti, S. (2013). The G-Quadruplex Augments Translation in the 5′ Untranslated Region of Transforming Growth Factor β2. Biochemistry, 52(9), 1528-1538. doi: 10.1021/bi301365g

Tiwari, S., Kumar, V., Jayaraj, G., Maiti, S., & Mapa, K. (2013). Unique Structural Modulation of a Non-Native Substrate by Cochaperone DnaJ. Biochemistry, 52(6), 1011-1018. doi: 10.1021/bi301543g

Mapa, K., Tiwari, S., Kumar, V., Jayaraj, G., & Maiti, S. (2012). Information Encoded in Non-Native States Drives Substrate-Chaperone Pairing. Structure, 20(9), 1562-1573. doi: 10.1016/j.str.2012.06.014

Mapa, K., Tiwari, S., Kumar, V., Jayaraj, G., & Maiti, S. (2012). Information Encoded in Non-Native States Drives Substrate-Chaperone Pairing. Structure, 20(9), 1562-1573. doi: 10.1016/j.str.2012.06.014

Kumar, S., Bose, D., Suryawanshi, H., Sabharwal, H., Mapa, K., & Maiti, S. (2011). Specificity of RSG-1.2 Peptide Binding to RRE-IIB RNA Element of HIV-1 over Rev Peptide Is Mainly Enthalpic in Origin. Plos ONE, 6(8), e23300. doi: 10.1371/journal.pone.0023300

Popov‐Čeleketić, D., Waegemann, K., Mapa, K., Neupert, W., & Mokranjac, D. (2011). Role of the import motor in insertion of transmembrane segments by the mitochondrial TIM23 complex. EMBO Reports, 12(6), 542-548. doi: 10.1038/embor.2011.72

Mapa, K., Sikor, M., Kudryavtsev, V., Waegemann, K., Kalinin, S., & Seidel, C. et al. (2010). The Conformational Dynamics of the Mitochondrial Hsp70 Chaperone. Molecular Cell, 38(1), 89-100. doi: 10.1016/j.molcel.2010.03.010

Sikor, M., Mapa, K., Kudryavtsev, V., Waegemann, K., Kalinin, S., & Seidel, C. et al. (2010). The Conformational Cycle of Mitochondrial Hsp70. Biophysical Journal, 98(3), 747a. doi: 10.1016/j.bpj.2009.12.4094

Blamowska, M., Sichting, M., Mapa, K., Mokranjac, D., Neupert, W., & Hell, K. (2010). ATPase Domain and Interdomain Linker Play a Key Role in Aggregation of Mitochondrial Hsp70 Chaperone Ssc1. Journal Of Biological Chemistry, 285(7), 4423-4431. doi: 10.1074/jbc.m109.061697

Mokranjac, D., Sichting, M., Popov-Čeleketić, D., Mapa, K., Gevorkyan-Airapetov, L., & Zohary, K. et al. (2009). Role of Tim50 in the Transfer of Precursor Proteins from the Outer to the Inner Membrane of Mitochondria. Molecular Biology Of The Cell, 20(5), 1400-1407. doi: 10.1091/mbc.e08-09-0934

Mapa, K., Sikor, M., Waegmann, K., Neupert, W., Mokranjac, D., & Lamb, D. (2009). Single Molecule Investigations of HSP70 Proteins. Biophysical Journal, 96(3), 556a. doi: 10.1016/j.bpj.2008.12.3654

Popov-Čeleketić, D., Mapa, K., Neupert, W., & Mokranjac, D. (2008). Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. The EMBO Journal. https://doi.org/10.1038/emboj.2008.79

Dhar, D., Mapa, K., Pudi, R. et al. Human ribosomal protein L18a interacts with hepatitis C virus internal ribosome entry site. Arch Virol 151, 509–524 (2006). https://doi.org/10.1007/s00705-005-0642-6